May 5, 2026

How Is Rejuran Different from Other Polynucleotides?

If you have been looking into skin boosters lately, chances are you have come across the term polynucleotides and more specifically, Rejuran. But with so many similar sounding treatments on the market, it is completely understandable to feel a little confused. What actually makes Rejuran different, and is it the right option for you?


What Are Polynucleotides?

Polynucleotides, often abbreviated to PN or PDRN, are molecules derived from DNA fragments, typically sourced from salmon or trout. When injected into the skin, they work by stimulating the skin's own repair and regeneration process. Think of them as a signal that tells your skin cells to get back to work: producing collagen, improving hydration, and healing damage at a cellular level.

They are increasingly popular in the UK as a science backed alternative to traditional fillers, because instead of adding volume, they help the skin genuinely improve from within.



So What Makes Rejuran Stand Out?

Not all polynucleotide products are made the same. Here is what sets Rejuran apart from other options on the market:


1. Its Origins and Purity

Rejuran is a Korean developed polynucleotide treatment that has been through rigorous clinical testing. It uses a highly purified form of PN extracted from wild caught salmon DNA, and its manufacturing process is tightly controlled, which means fewer impurities and a more consistent results.


2. Molecular Weight Matters

One of the most important but often overlooked differences between polynucleotide products is their molecular weight. Rejuran uses long chain polynucleotides, which means the molecules are larger and tend to remain in the skin for longer, working gradually and effectively over time.


3. Skin Repair vs. Hydration Focus

Many polynucleotide treatments are formulated primarily to hydrate the skin, similar to a skin booster. Rejuran, on the other hand, is specifically engineered to repair and regenerate the skin at a deeper level. It is particularly brilliant for improving skin texture, reducing pore size, fading acne scarring, and restoring elasticity that has been lost due to aging or sun damage.


4. Proven Clinical Track Record

Rejuran has been used in Korea and across Asia for well over a decade, with an extensive body of clinical data to support its safety and efficacy. It is one of the most well researched polynucleotide treatments available, which is why it has earned the trust of practitioners and patients alike.



How Does Rejuran Compare to Other Popular Injectables?

You might be wondering how Rejuran compares to treatments like Profhilo or other skin boosters you may have heard of. The key difference is intent. While products like Profhilo are primarily hyaluronic acid-based and focus on deep hydration and structural improvement, Rejuran works on a biological level to essentially reset and repair the skin. They are not rivals. In fact, they are often used alongside one another for a more comprehensive result.



Who Is Rejuran Best Suited For?

Rejuran tends to work particularly well for people who are dealing with one or more of the following:

•        Dull, tired looking skin that lacks vitality

•        Fine lines and early signs of aging

•        Enlarged pores and uneven skin texture

•        Acne scarring or post inflammatory marks

•        Skin that has been damaged by sun exposure

•        Anyone wanting a natural, gradual improvement without dramatic change

It is suitable for most skin types and tones, and there is no required downtime, making it a popular lunchtime treatment.



What to Expect at Dr L'Art Aesthetic Clinic

At Dr L'Art in London, Rejuran is administered by experienced practitioners who take the time to understand your skin concerns before recommending the most suitable treatment plan. We offer Rejuran as both a standalone treatment and as part of our Korean Glass Skin packages, which combine multiple regenerative techniques for a full glow result.


Most clients notice a visible improvement in skin quality within two to four weeks of their first session, with optimal results typically seen after a course of two to three treatments.


Curious whether Rejuran is right for your skin? Book a consultation at Dr L'Art, we'd love to help you find your best skin yet. View our current offers at drlart.co.uk/special-offers-at-dr-lart

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营业时间

周一/二/三/五

10:00am – 6:30pm

周四

11:30am – 8:00pm

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10:00am – 6:00pm

周日

不营业

关注我们的Instagram

© 2025 Dr L'Art, All Rights Reserved. 

联系方式
营业时间

周一/二/三/五

10:00am – 6:30pm

周四

11:30am – 8:00pm

周六

10:00am – 6:00pm

周日

不营业

关注我们的Instagram

© 2025 Dr L'Art, All Rights Reserved.